HA15
SIGMA/SML2118 - ≥98% (HPLC)
Synonym: N-
CAS Number: 1609402-14-3
Empirical Formula (Hill Notation): C23H22N4O3S2
Molecular Weight: 466.58
MDL Number: MFCD30377202
Linear Formula: C23H22N4O3S2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
SMILES string | CC(NC1=NC(C2=CC=CC(NS(C3= |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | HA15 is a selective ligand of BiP/GRP78/HSPA5 chaperone that increases ER stress, leading to autophagic and apoptotic cell death in varies cancer cell lines including melanoma cells. HA15 inhibits inhibit the ATPase activity of BiP. HA15 inhibits tumor development in mice injected with A375 melanoma cells. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |