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Solifenacin succinate

SIGMA/SML2141 - ≥98% (HPLC)

Synonym: (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl 3,4­dihydro-1-phenyl-2(1H)-iso-quinolinecarboxylate succinate; YM905

CAS Number: 242478-38-2
Empirical Formula (Hill Notation): C23H26N2O2 · C4H6O4
Molecular Weight: 480.55
MDL Number: MFCD00954234
Linear Formula: C23H26N2O2 · C4H6O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML2141-25MG 25 mg
 $57.00
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45-SML2141-100MG 100 mg
 $190.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C23H26N2O2.C4H6O4/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19;5-3(6)1-2-4(7)8/h1-9,18,21-22H,10-16H2;1-2H2,(H,5,6)(H,7,8)/t21?,22-;/m0./s1
InChI key RXZMMZZRUPYENV-DZSUWJOWSA-N
optical activity [α]/D +35 to +45°, c = 1 in H2O
Quality Level 100 
SMILES string OC(CCC(O)=O)=O.O=C(O[C@H]1CN2CCC1CC2)N3[C@@H](C4=CC=CC=C4)C5=CC=CC=C5CC3
solubility H2O: 2 mg/mL, clear
storage condition desiccated
storage temp. 2-8°C
Biochem/physiol Actions: Solifenacin succinate (SOL) blocks the cholinergic signals to M3 receptors by inhibiting the muscarinic M3 receptors in the bladder. This action prevents the contractions of the detrusor muscles in the urinary bladder wall, leading to relaxing the bladder as well as decreasing urinary urgency and nocturia. Thus, SOL is a widely used antimuscarinic agent for treating the contraction of the overactive bladder.
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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