CLP290
SIGMA/SML2172 - ≥98% (HPLC)
Synonym: [5-
CAS Number: 1181083-81-7
Empirical Formula (Hill Notation): C19H21FN4O3S
Molecular Weight: 404.46
MDL Number: MFCD28166314
Linear Formula: C19H21FN4O3S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
SMILES string | FC1=CC=C(/C=C2C(N=C(N3NCC |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | CLP290 is a small molecule enhancer of KCC2 activity. It is an orally active and more bioavailable precursor of the selective K+-Cl- cotransporter KCC2 activator CLP257. CLP290 was recently shown to restore Cl- transport and rescue morphine-induced hyperalgesia (MIH) in morphine-treated rats. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |