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Kevetrin hydrochloride

SIGMA/SML2184 - ≥98% (HPLC)

Synonym: Kevetrin hydrochloride; 4-Isothioureidobutyronitrile hydrochloride; Carbamimidothioic acid 3-cyanopropyl ester hydrochloride; NSC 525990 HCl

CAS Number: 66592-89-0
Empirical Formula (Hill Notation): C5H9N3S · HCl
Molecular Weight: 179.67
MDL Number: MFCD22572767
Linear Formula: C5H9N3S · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML2184-5MG 5 mg
 $102.00
1/EA		 Add To Favorites
45-SML2184-25MG 25 mg
 $329.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
SMILES string NC(SCCCC#N)=N.Cl
solubility H2O: 2 mg/mL, clear
storage condition desiccated
storage temp. −20°C
Biochem/physiol Actions: Kevetrin is an activator/stabilizer of wild type p53 tumor suppressor protein in human lung carcinoma and ovarian cancer cells that induces cell cycle arrest and apoptosis. Additionally Kevetrin down-regulates oncogenic mutant p53 in OVCAR-3 ovarian cancer cells. Kevetrin inhibits tumor growth in xenograft model of ovarian cancer.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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