Kevetrin hydrochloride
SIGMA/SML2184 - ≥98% (HPLC)
Synonym: Kevetrin hydrochloride; 4-
CAS Number: 66592-89-0
Empirical Formula (Hill Notation): C5H9N3S · HCl
Molecular Weight: 179.67
MDL Number: MFCD22572767
Linear Formula: C5H9N3S · HCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
SMILES string | NC(SCCCC#N)=N.Cl |
solubility | H2O: 2 mg/mL, clear |
storage condition | desiccated |
storage temp. | −20°C |
Biochem/physiol Actions: | Kevetrin is an activator/stabilizer of wild type p53 tumor suppressor protein in human lung carcinoma and ovarian cancer cells that induces cell cycle arrest and apoptosis. Additionally Kevetrin down-regulates oncogenic mutant p53 in OVCAR-3 ovarian cancer cells. Kevetrin inhibits tumor growth in xenograft model of ovarian cancer. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |