RL5a
SIGMA/SML2187 - ≥98% (HPLC)
Synonym: N2-
CAS Number: 133671-66-6
Empirical Formula (Hill Notation): C17H19N3O
Molecular Weight: 281.35
MDL Number: MFCD00929354
Linear Formula: C17H19N3O
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to very dark brown |
form | powder |
InChI | 1S/C17H19N3O/c1-20(2)10-9 |
InChI key | CRGKLHXVNVZAPA-UHFFFAOYSA |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | RL5a is a potent inhibitor of the replication licensing system in human cells. RL5a blocks the binding of the origin recognition complex (ORC) to origin DNA, which is required interaction for licensing. RL5a appears to act as noncompetitive inhibitor of ORC with respect to ATP. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |