Synonym: (-)-Nuciferine; (6aR)-5,6,6a,7-Tetrahydro-1,2-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline; (R)-1,2-Dimethoxyaporphine; (R)-Nuciferine; 1,2-Dimethoxy-6a-aporphine; D-(-)-Nuciferine; Nuciferin; Sanjoinine E; 1,2-Dimethoxy 6aβ-aporphine; Sanjoinine E
CAS Number: 475-83-2
Empirical Formula (Hill Notation): C19H21NO2
Molecular Weight: 295.38
MDL Number: MFCD01664592
Linear Formula: C19H21NO2
Product Type: Chemical
assay |
≥98% (HPLC) |
biological source |
Nelumbo nucifera |
color |
white to beige |
form |
powder |
InChI |
1S/C19H21NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3/t15-/m1/s1 |
InChI key |
ORJVQPIHKOARKV-OAHLLOKOSA-N |
optical activity |
[α]/D -145 to -165°, c = 0.5 in ethanol |
SMILES string |
[H][C@]1(C2=C3C(OC)=C(OC)C=C2CCN1C)CC4=C3C=CC=C4 |
solubility |
DMSO: 2 mg/mL, clear (warmed) |
storage temp. |
2-8°C |
Biochem/physiol Actions: |
Nuciferine is a major active component from lotus leaf that produces antipsychotic-like effect in rodents. Nuciferine is a potent inverse agonist at human 5-HT7 receptor. Nuciferine attenuates fructose-induced hyperuricemia, dyslipidemia and systemic inflammation in rats. |
Symbol |
GHS06 |
Signal word |
Danger |
Hazard statements |
H301 |
Precautionary statements |
P301 + P330 + P331 + P310 |
RIDADR |
UN 1544PSN1 6.1 / PGIII |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
2-8°C |
UNSPSC |
12352200 |