Advanced Search



1S,3R-RSL 3

SIGMA/SML2234 - ≥98% (HPLC)

Synonym: (1S, 3R)-2-(2-Chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester

CAS Number: 1219810-16-8
Empirical Formula (Hill Notation): C23H21ClN2O5
Molecular Weight: 440.88
MDL Number: MFCD30187526
Linear Formula: C23H21ClN2O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML2234-5MG 5 mg
 $115.00
1/EA		 Add To Favorites
45-SML2234-25MG 25 mg
 $462.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to beige
form powder
solubility DMSO: 2 mg/mL, clear
storage temp. −20°C
Application: 1S,3R-RSL 3 has been used:
• as a glutathione peroxidase 4 (GPX4) inhibitor to study its effects on cell death in subventricular glioblastoma multiforme (GBM) lines
• GPX4 inhibitor and ferroptosis inducer to study its effects on cardiomyocyte death and heart failure in mice
• as a ferroptosis inducer in HT-1080 cellsin cell viability assay
Biochem/physiol Actions: RSL3 is an inducer of ferroptosis. It acts by a different method than erastin to induce ferroptosis by inhibiting glutathione peroxidase 4 (GPX4).
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Year Price Updates

We are currently working diligently to update our website pricing information for the New Year. If you place an order, you will be acknowledged with any corrected pricing. If you'd like the most current information sooner, please don't hesitate to drop us an email or give us a call and we'd be happy to assist. Thank you for your patience while we are updating.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top