CL075
SIGMA/SML2235 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 256922-53-9
Empirical Formula (Hill Notation): C13H13N3S
Molecular Weight: 243.33
MDL Number: MFCD09998898
Linear Formula: C13H13N3S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Application: | CL075 has been used to activate the monocyte-derived dendritic cells (DCs) to demonstrate the ability of DCs to induce cell death. |
Biochem/physiol Actions: | CL075 is a selective agonist of Toll-like receptor-8 (TLR-8) with immunostimulant activity. It showed an EC50 value of 400nM for IRF-NFΚB stimulation in TLR8 compared to 4 μM for TLR7. |
Biochem/physiol Actions: | CL075 is a thiazoloquinolone derivative. It might influence tumor development. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |