Synonym: 6-O-Butanoylcastanospermine; 6-O-Butyrylcastanospermine; BuCast; Butanoic acid (1S,6S,7S,8R,8aR)-octahydro-1,7,8-trihydroxy-6-indolizinyl ester; Butanoic acid [1S-(1α,6β,7α,8β,8aβ)]-octahydro-1,7,8-trihydroxy-6-indolizinyl ester; MDL 28,574; MDL 28574; MDL-28574
CAS Number: 121104-96-9
Empirical Formula (Hill Notation): C12H21NO5
Molecular Weight: 259.30
MDL Number: MFCD00886617
Linear Formula: C12H21NO5
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white to beige |
| form |
powder |
| InChI |
1S/C12H21NO5/c1-2-3-9(15)18-8-6-13-5-4-7(14)10(13)12(17)11(8)16/h7-8,10-12,14,16-17H,2-6H2,1H3/t7-,8-,10+,11+,12+/m0/s1 |
| InChI key |
HTJGLYIJVSDQAE-VWNXEWBOSA-N |
| SMILES string |
O[C@@H]1[C@@H](OC(CCC)=O)CN2[C@@]([C@@H](O)CC2)([H])[C@H]1O |
| solubility |
H2O: 2 mg/mL, clear |
| storage condition |
desiccated |
| |
under inert gas |
| storage temp. |
−20°C |
| Biochem/physiol Actions: |
Celgosivir is a prodrug of natural bicyclic iminosugar castanospermine that exhibits antiviral activity in vivo including HCV and dengue. Celgosivir is an inhibitor of α-glucosidases, which inhibits glycoprotein processing in cell culture. Apparently inhibition of α-glucosidases within infected cell prevents secretion of virus. |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
−20°C |
| UNSPSC |
12352200 |
