Tipelukast
SIGMA/SML2369 - ≥98% (HPLC)
Synonym: 4-
CAS Number: 125961-82-2
Empirical Formula (Hill Notation): C29H38O7S
Molecular Weight: 530.67
MDL Number: MFCD00886138
Linear Formula: C29H38O7S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C29H38O7S/c1-5-9-23-25 |
InChI key | KPWYNAGOBXLMSE-UHFFFAOYSA |
SMILES string | CCCC1=C(SCCCOC2=C(CCC)C(O |
solubility | DMSO: 2 mg/mL, clear |
storage condition | desiccated |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Tipelukast is a Leukotriene D4 (LTD4) receptor antagonist and an inhibitor of 5-lipoxygenase (5-LO) and also phosphodiesterases PDE3 and PDE4. It has been found to have antifibrotic and anti-inflammatory activity. Tipelukast has been investigated as a possible treatment for nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |