Synonym: (3β,5β,8α,9β,10α,13α)-3β-(acetyloxy)-4,4,8,12,16-pentamethyl-15,17,19-trioxoandrost-11-ene-14-carboxylic acid methyl ester
CAS Number: 174232-42-9
Empirical Formula (Hill Notation): C28H38O7
Molecular Weight: 486.60
MDL Number: MFCD28898503
Linear Formula: C28H38O7
Product Type: Chemical
assay |
≥95% (HPLC) |
color |
white to beige |
form |
powder |
InChI |
1S/C28H38O7/c1-15-13-19-25(6,28(23(33)34-8)22(32)16(2)21(31)26(15,28)7)11-9-18-24(4,5)20(35-17(3)30)10-12-27(18,19)14-29/h13-14,16,18-20H,9-12H2,1-8H3/t16?,18?,19-,20?,25?,26+,27+,28?/m0/s1 |
InChI key |
GRBXNADBNJGZRK-BCMOVVIDSA-N |
storage temp. |
−20°C |
Biochem/physiol Actions: |
Andrastin A is a meroterpenoid protein farnesyltransferase inhibitor with anticancer activity. It has been shown to inhibit the farnesyltransferase activity of the oncogenic Ras proteins and inhibit the efflux of anticancer drugs from multidrug-resistant cancer cells. |
Biochem/physiol Actions: |
Farnesyltransferase inhibitor with anticancer activity; mycotoxin |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥95% (HPLC) |
Storage Temp. |
−20°C |
UNSPSC |
12352200 |