JNS 1-40
SIGMA/SML2390 - ≥95% (HPLC)
Synonym: N-
CAS Number: 2241773-03-3
Empirical Formula (Hill Notation): C17H16ClNO3
Molecular Weight: 317.77
Linear Formula: C17H16ClNO3
Product Type: Chemical
assay | ≥95% (HPLC) |
color | white to beige |
form | powder |
SMILES string | O=C(CCl)N(CC1=CC=CC=C1)C2 |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | JNS 1-40 is a potent and selective cysteine-reactive covalent ligand of regulatory subunit PPP2R1A of the tumor-suppressor protein phosphatase 2A (PP2A) that activate PP2A in vitro and in vivo. JNS 1-40 targets C377 of PPP2R1A and inhibits breast cancer proliferation, and in vivo tumor growth. |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |