ML327
SIGMA/SML2399 - ≥98% (HPLC)
Synonym: 1,2-
CAS Number: 1883510-31-3
Empirical Formula (Hill Notation): C19H18N4O4
Molecular Weight: 366.37
MDL Number: MFCD31619239
Linear Formula: C19H18N4O4
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | ML327 is a regulator of E-cadherin transcription that restores E-cadherin expression in cancer cell lines and partially reverses Epithelial-to-Mesenchymal Transition (EMT). It is a potent inducer of mesenchymal-to-epithelial transition (MET) in epithelial cancers. Apparently ML327 blocks MYC expression in neuroblastomas. It induces apoptosis in cancer cells and sensitizes Ewing sarcoma cells to TRAIL. |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |