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WYC-209

SIGMA/SML2402 - ≥98% (HPLC)

Synonym: 2-[2-(3,4-Dihydro-4,4-dimethyl-1-oxido-2H-1-benzothiopyran-6-yl)ethynyl-5-pyrimidinecarboxylic acid, ethyl ester

CAS Number: 2131803-90-0
Empirical Formula (Hill Notation): C20H20N2O3S
Molecular Weight: 368.45
Linear Formula: C20H20N2O3S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML2402-5MG 5 mg
$97.70
1/EA
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45-SML2402-25MG 25 mg
$316.00
1/EA
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assay ≥98% (HPLC)
color white to beige
form powder
SMILES string O=S1CCC(C)(C)C2=C1C=CC(C#CC3=NC=C(C(OCC)=O)C=N3)=C2
solubility DMSO: 2 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: Synthetic retinoid with antiproliferative activity
Biochem/physiol Actions: WYC-209 is a synthetic retinoid with antiproliferative activity and better inhibition of cancer cell growth and proliferation than Tazarotene or ATRA (all-trans-retinoic acid). WYC-209 was shown to inhibit proliferation of malignant murine melanoma tumor-repopulating cells (TRCs) with an IC50 value of 190 nM and also inhibited proliferation of TRCs of human melanoma, lung cancer, ovarian cancer, and breast cancer in culture.
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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