Synonym: 2-[2-(3,4-Dihydro-4,4-dimethyl-1-oxido-2H-1-benzothiopyran-6-yl)ethynyl-5-pyrimidinecarboxylic acid, ethyl ester
CAS Number: 2131803-90-0
Empirical Formula (Hill Notation): C20H20N2O3S
Molecular Weight: 368.45
Linear Formula: C20H20N2O3S
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
white to beige |
form |
powder |
SMILES string |
O=S1CCC(C)(C)C2=C1C=CC(C#CC3=NC=C(C(OCC)=O)C=N3)=C2 |
solubility |
DMSO: 2 mg/mL, clear |
storage temp. |
2-8°C |
Biochem/physiol Actions: |
Synthetic retinoid with antiproliferative activity |
Biochem/physiol Actions: |
WYC-209 is a synthetic retinoid with antiproliferative activity and better inhibition of cancer cell growth and proliferation than Tazarotene or ATRA (all-trans-retinoic acid). WYC-209 was shown to inhibit proliferation of malignant murine melanoma tumor-repopulating cells (TRCs) with an IC50 value of 190 nM and also inhibited proliferation of TRCs of human melanoma, lung cancer, ovarian cancer, and breast cancer in culture. |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98% (HPLC) |
Storage Temp. |
2-8°C |
UNSPSC |
12352200 |