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Sophocarpine

SIGMA/SML2422 - ≥95% (HPLC)

Synonym: (-)-Sophocarpine; 13,14-Didehydromatridin-15-one; SC

CAS Number: 6483-15-4
Empirical Formula (Hill Notation): C15H22N2O
Molecular Weight: 246.35
MDL Number: MFCD00274555
Linear Formula: C15H22N2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML2422-25MG 25 mg
 $49.00
1/EA		 Add To Favorites
45-SML2422-125MG 125 mg
 $149.00
1/EA		 Add To Favorites

 

assay ≥95% (HPLC)
biological source Sophora alopecuroides
color white to beige
form powder
InChI 1S/C15H22N2O.BrH/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14;/h1,7,11-13,15H,2-6,8-10H2;1H/t11-,12+,13+,15-;/m0./s1
InChI key NBBQEIQEBNYSFK-PUILLJIJSA-N
optical activity [α]/D -26 to -35°, c = 0.5 in ethanol
solubility DMSO: 2 mg/mL, clear
storage temp. −20°C
Biochem/physiol Actions: Sophocarpine is a natural product found to have anti-inflammatory, anti-cancer, and antiviral activity. Sophocarpine was active in an mouse xenograft model. It inhibited growth of head and neck squamous cell carcinomas by downregulation of miR-21 expression. Sophocarpine was also shown to protecs mice from a form of hepatitis by inhibiting the IFNg/STAT1 pathway.
Purity ≥95% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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