Sophocarpine
SIGMA/SML2422 - ≥95% (HPLC)
Synonym: (-)-Sophocarpine; 13,14-
CAS Number: 6483-15-4
Empirical Formula (Hill Notation): C15H22N2O
Molecular Weight: 246.35
MDL Number: MFCD00274555
Linear Formula: C15H22N2O
Product Type: Chemical
assay | ≥95% (HPLC) |
biological source | Sophora alopecuroides |
color | white to beige |
form | powder |
InChI | 1S/C15H22N2O.BrH/c18-14-7 |
InChI key | NBBQEIQEBNYSFK-PUILLJIJSA |
optical activity | [α]/D -26 to -35°, c = 0.5 in ethanol |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | Sophocarpine is a natural product found to have anti-inflammatory, anti-cancer, and antiviral activity. Sophocarpine was active in an mouse xenograft model. It inhibited growth of head and neck squamous cell carcinomas by downregulation of miR-21 expression. Sophocarpine was also shown to protecs mice from a form of hepatitis by inhibiting the IFNg/STAT1 pathway. |
Symbol | ![]() |
Signal word | Danger |
Hazard statements | H301 |
Precautionary statements | P264 - P270 - P301 + P310 + P330 - P405 - P501 |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |