GNF-4877
SIGMA/SML2664 - ≥98% (HPLC)
Synonym: (3R)
CAS Number: 2041073-22-5
Empirical Formula (Hill Notation): C25H27FN6O4
Molecular Weight: 494.52
Linear Formula: C25H27FN6O4
Product Type: Chemical
assay | ≥98% (HPLC) |
color | faint yellow to dark orange |
form | powder |
SMILES string | NC1=NC=C(C2=CC(OC(C)C)=CC |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | GNF-4877 is an orally available dual inhibitor of Dyrk1a and Gsk3b that induces proliferation of functional primary human and rodent β-cells. GNF4877 reduces non-fasting blood glucose levels in a mouse model of T1D. |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |