RG1534
SIGMA/SML2762 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 150096-77-8
Empirical Formula (Hill Notation): C19H16ClN5O3
Molecular Weight: 397.82
Linear Formula: C19H16ClN5O3
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
SMILES string | NC1=CC=CC=C1C(NC(NC2=CC(C |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | RG1534 is an inhibitor of hTERT promoter activity that selectively targets G-hairpin stem loop of the human telomerase reverse transcriptase gene (hTERT) that downregulates hTERT expression. RG1534 induces mitochondrial defects, oxidative stress, DNA damage and apoptosis in cancer cell while sparing normal cells |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |