Amonafide
SIGMA/SML2771 - ≥98% (HPLC)
Synonym: 5-
CAS Number: 69408-81-7
Empirical Formula (Hill Notation): C16H17N3O2
Molecular Weight: 283.33
MDL Number: MFCD00866438
Linear Formula: C16H17N3O2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | Amonafide, a naphthalimides DNA intercalator, is a potent topoisomerase II inhibitor that inhibits tumor proliferation and progression. It appears that Amonafide inhibits melanoma progression through inhibition of the AKT/mTOR signaling pathway. |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |