Tarenflurbil
SIGMA/SML2841 - ≥98% (HPLC)
Synonym: (R)-(−)-2-Fluoro-α-methyl-4-biphenylacetic acid; αR)-2-Fluoro-α-methyl[1,1′-biphenyl]-4-acetic acid; (-)-(R)-Flurbiprofen; (2R)
CAS Number: 51543-40-9
Empirical Formula (Hill Notation): C15H13FO2
Molecular Weight: 244.26
MDL Number: MFCD00869714
Linear Formula: C6H5C6H3(F)CH(CH3)CO2H
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C15H13FO2/c1-10(15(17) |
InChI key | SYTBZMRGLBWNTM-SNVBAGLBSA |
Quality Level | 100 ![]() |
SMILES string | C[C@@H](C(O)=O)c1ccc(c(F) |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Tarenflurbil (or R-flurbiprofen) is an R enantiomer of racemic NSAID flurbiprofen that does not inhibit either cyclooxygenase 1 (COX-1) or cyclooxygenase 2 (COX-2). Tarenflurbil potently reduces levels of beta amyloid in human cells through direct inhibition of γ-secretase. |
Symbol | ![]() ![]() |
Signal word | Danger |
Hazard statements | H301 + H311 - H317 - H361d |
Precautionary statements | P201 - P280 - P301 + P310 + P330 - P302 + P352 + P312 |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |