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MAC-545496

SIGMA/SML2901 - ≥98% (HPLC)

Synonym: N-(5-chloropyridin-2-ylcarbamothioyl)-3-nitro-4-(piperidin-1-yl)benzamide; N-[[(5-chloro-2-pyridinyl)amino]thioxomethyl]-3-nitro-4-(1-piperidinyl)benzamide

CAS Number: 838810-96-1
Empirical Formula (Hill Notation): C18H18ClN5O3S
Molecular Weight: 419.89
MDL Number: MFCD05848166
Linear Formula: C18H18ClN5O3S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML2901-5MG 5 mg
$75.40
1/EA
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45-SML2901-25MG 25 mg
$306.00
1/EA
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assay ≥98% (HPLC)
color faint yellow to dark orange
form powder
Quality Level 100 
solubility DMSO: 2 mg/mL, clear
storage temp. 2-8°C
Biochem/physiol Actions: MAC-545496 is a potent and selective inhibitor of glycopeptide-resistance-associated protein R (GraR) that displays antivirulence and antimicrobial adjuvant properties. MAC-545496 reverses β-lactam resistance in Methicillin-resistant strains (MRSA) and synergizes with cationic antimicrobial peptides (CAMPs). It also potentiates the effects of Cefuroxime and Oxacillin MRSA strains. MAC-545496 has no effect on commensal S. epidermidis and Gram-negative bacteria such as P. aeruginosa.
WGK Germany WGK 3
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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