Synonym: 2-[[[4-(1,2-Dihydro-2-methyl-1-oxo-2,7-naphthyridin-4-yl)-2,6-dimethoxyphenyl]methyl]methylamino]-N-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]acetamide Hydrochloride; Naphthiridinone degrader 6 Hydrochloride
Empirical Formula (Hill Notation): C40H45N7O10 · xHCl
Molecular Weight: 783.83 (free base basis)
Linear Formula: C40H45N7O10 · xHCl
Product Type: Chemical
assay |
≥97% (HPLC) |
color |
white to beige |
form |
powder |
Quality Level |
100 ![External link](https://krackeler.com/images/sigma/ext-link.gif) |
solubility |
H2O: 2 mg/mL, clear |
storage temp. |
−20°C |
Biochem/physiol Actions: |
dBRD9 is a cell permeable, potent and selective BRD9-directed chemical degrader that bridges the BRD9 bromodomain and the cereblon E3 ubiquitin ligase complex. dBRD9 exhibits a potent anti-proliferative activity in human AML lines. |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥97% (HPLC) |
Storage Temp. |
−20°C |
UNSPSC |
12352200 |