Biotin-aniline
SIGMA/SML2946 - ≥98% (HPLC)
Synonym: (3aS,4S,6aR)
CAS Number: 769933-15-5
Empirical Formula (Hill Notation): C18H26N4O2S
Molecular Weight: 362.49
Linear Formula: C18H26N4O2S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
SMILES string | O=C(CCCC[C@@H]1SC[C@]([H] |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Biotin-aniline (Btn-An) is a superior substrate than biotinyl tyramide (biotin-phenol; BP) for APEX2-mediated proximity labeling of RNA (∼25-fold higher by dot blot with 0.5 mM substrate and 0.4-10 μg RNA/dot). Btn-An specifically labels mitochondrial, but not cytoplasmic, mRNAs in live HEK293T stable line expressesing APEX2 in the mitochondrial matrix (mito-APEX2). |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |