E7820
SIGMA/SML2950 - ≥98% (HPLC)
Synonym: 3-
CAS Number: 289483-69-8
Empirical Formula (Hill Notation): C17H12N4O2S
Molecular Weight: 336.37
MDL Number: MFCD09833234
Linear Formula: C17H12N4O2S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | E7820 (NSC 719239) is an orally available anticancer and antiangiogenic agent that inhibits VEGF-2 or FGF-2-induced tube formation of HUVEC cells through the suppression of integrin α2. E7820 promotes selective proteasomal degradation of the U2AF-related splicing factor CAPERα (coactivator of activating protein-1 and estrogen receptors) by ubiquitination and degradation via CRL4DCAF15. |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |