Gabexate mesylate
SIGMA/SML2964 - ≥97% (HPLC)
Synonym: Gabexate mesylate; 4-
CAS Number: 56974-61-9
Empirical Formula (Hill Notation): C16H23N3O4 · CH4O3S
Molecular Weight: 417.48
MDL Number: MFCD00210299
Linear Formula: C16H23N3O4 · CH4O3S
Product Type: Chemical
assay | ≥97% (HPLC) |
color | white to beige |
form | powder |
InChI | 1S/C16H23N3O4.CH4O3S/c1-2 |
InChI key | DNTNDFLIKUKKOC-UHFFFAOYSA |
Quality Level | 100 ![]() |
SMILES string | CS(O)(=O)=O.CCOC(=O)c1ccc |
solubility | H2O: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Gabexate mesylate is a competitive inhibitor of serine proteases that displays high selectivity for TMPRSS2 (Transmembrane protease serine 2) (IC50 = 130 nM) with little or no activity towards several MMPs, caspases and USPs (>> 10 μM). Gabexate mesylate was reported to decrease inflammatory cytokines production and be useful as an anticoagulant. |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥97% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |