BIX02188
SIGMA/SML2984 - ≥98% (HPLC)
Synonym: (3Z)
CAS Number: 334949-59-6
Empirical Formula (Hill Notation): C25H24N4O2
Molecular Weight: 412.48
MDL Number: MFCD18157583
Linear Formula: C25H24N4O2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | BIX02188 is a potent and selective inhibitor of MEK5 with IC50 of 4.3 nM. BIX02188 also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2. |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |