SR-301
SIGMA/SML2996 - ≥98% (HPLC)
Synonym: 6-
CAS Number: 2375419-35-3
Empirical Formula (Hill Notation): C17H11F6N5O2
Molecular Weight: 431.29
Linear Formula: C17H11F6N5O2
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
SMILES string | O=C(C1=NN=C(N2C=NC=C2)C=C |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | SR-301 is an orally bioavailable analog of the selective STING agonist SR-717. SR-301 shows higher potency than SR-717 by THP1-based ISRE reporter assay (EC50 = 0.6 vs. 2.1 μM, respectively) and shows good antitumor efficacy when administered orally in a murine B16.F10 melanoma tumor model in vivo (15 mg/kg/day p.o.). |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |