Belinostat
SIGMA/SML3010 - ≥98% (HPLC)
Synonym: (2E)
CAS Number: 866323-14-0
Empirical Formula (Hill Notation): C15H14N2O4S
Molecular Weight: 318.35
MDL Number: MFCD08064035
Linear Formula: C15H14N2O4S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | Belinostat (PX105684; PXD101) is a potent, hydroxamate class pan-selective histone deacetylases (HDACs) inhibitor (IC50: class I HDAC1/2/3/8 = 41/125/30/216 nM, class IIA HDAC4/7/9 = 115/67/128 nM, class IIB HDAC6 = 82 nM) with anti-cancer efficacy in vitro and in vivo. |
Symbol | ![]() |
Signal word | Danger |
Hazard statements | H340 - H361f - H373 |
Precautionary statements | P201 - P202 - P260 - P280 - P308 + P313 - P405 |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |