TH1834
SIGMA/SML3018 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 2108830-09-5
Empirical Formula (Hill Notation): C33H40N6O3 · 2HCl
Molecular Weight: 641.63
MDL Number: MFCD28396413
Linear Formula: C33H40N6O3 · 2HCl
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
SMILES string | O=C(O)CN1N=C(C2=CC=C(CN(C |
solubility | H2O: 2 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | TH1834 is a cell penetrant, potent and selective histone acetyltransferase (HAT) Tip60 inhibitor that interact with active binding pocket of Tip60. TH1834 induces apoptosis and increased unrepaired DNA damage in breast and prostate cancer cell lines but not control MCF10A cells. |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |