TH1760
SIGMA/SML3019 - ≥98% (HPLC)
Synonym: 6-
CAS Number: 2567914-01-4
Empirical Formula (Hill Notation): C20H18N4O5S
Molecular Weight: 426.45
Linear Formula: C20H18N4O5S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
SMILES string | O=S(C1=CC(O2)=C(C=C1)NC2= |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | TH1760 is a cell penetrant, potent and selective inhibitor of NUDT15 (NUDIX-type 15) that directly binds into the NUDT15 catalytic pocket. TH1760 sensitized cells to 6-thioguanine. |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |