Synonym: (betaR,deltaR)-2-(p-Fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoate, calcium salt (2:1) trihyddrate; [R-(R*, R*)]-2-(4-Fluorophenyl)-β, δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1Hpyrrole-1-heptanoic acid, calcium salt (2:1) trihydrate
CAS Number: 344423-98-9
Empirical Formula (Hill Notation): C66H68F2N4O10 · Ca · 3H2O
Molecular Weight: 1209.39
Linear Formula: C66H68F2N4O10 · Ca · 3H2O
Product Type: Chemical
assay |
≥98% (HPLC) |
color |
white to beige |
form |
powder |
optical activity |
[α]/D -9.0 to -5.0°, c = 0.5 in DMSO |
Quality Level |
100 ![External link](https://krackeler.com/images/sigma/ext-link.gif) |
SMILES string |
O=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C2=CC=C(C=C2)F)=C1C3=CC=CC=C3)NC4=CC=CC=C4.[Ca+2].[3.0H2O] |
solubility |
DMSO: 2 mg/mL, clear |
storage condition |
protect from light |
storage temp. |
room temp |
Biochem/physiol Actions: |
Atorvastatin calcium salt trihydrate is a specific inhibitor of β-Hydroxy β-methylglutaryl-CoA (HMG-CoA) reductase. HMG-CoA reductase is the enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an early step in cholesterol biosynthesis. Atorvastatin is used in the treatment of hypercholesterolemia. |
Purity |
≥98% (HPLC) |
Storage Temp. |
room temp |
UNSPSC |
12352200 |