BSJ-04-122
SIGMA/SML3061 - >97% (HPLC)
Synonym: N-
CAS Number: 2513289-74-0
Empirical Formula (Hill Notation): C15H12ClN5O
Molecular Weight: 313.74
Linear Formula: C15H12ClN5O
Product Type: Chemical
assay | >97% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | BSJ-04-122 is a cell penetrant, potent and selective covalent inhibitor of MKK4 and MKK7 (MAP2K4/7) that binds to Cys247 of MKK4. It potently inhibits JNK phosphorylation. BSJ-04-122 exhibits antiproliferative effects against triple-negative breast cancer cells. Also, BSJ-04-122 enhances antiproliferative activity of JNK-IN-8. |
Purity | >97% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |