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MR6-31-2

SIGMA/SML3242 - ≥98% (HPLC)

Synonym: 2-(4-Chlorobenzyl)benzo[d][1,2]selenazol-3(2H)-one; 2-[(4-Chlorophenyl)methyl]-1,2-benzisoselenazol-3(2H)-one

Empirical Formula (Hill Notation): C14H10ClNOSe
Molecular Weight: 322.65
Linear Formula: C14H10ClNOSe
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-SML3242-25MG
No Price  
45-SML3242-5MG
No Price  

 

assay ≥98% (HPLC)
color white to beige
form powder
Quality Level 100 
SMILES string O=C1N(CC2=CC=C(Cl)C=C2)[Se]C3=CC=CC=C31
storage temp. 2-8°C
Biochem/physiol Actions: MR6-31-2, a CNS penetrant ebselen analog, is a potent inhibitor of SARS-CoV-2 Mpro that bind at the Mpro catalytic site. MR6-31-2 donates a selenium atom, forming a covalent bond and blocking the histidine-Cys catalytic dyad. It exhibits good neuroprotective effects and low cytotoxicity in cell-based and mouse models of motor neuron disease. MR6-31-2 covalently binds to A4V superoxide dismutase-1 (SOD1) and promotes its thermal stability.
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352107

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