Stannsoporfin
SIGMA/SML3260 - ≥98% (HPLC)
Synonym: B 992; Dichloro[7,12-
CAS Number: 106344-20-1
Empirical Formula (Hill Notation): C34H36Cl2N4O4Sn
Molecular Weight: 754.29
Linear Formula: C34H36Cl2N4O4Sn
Product Type: Chemical
assay | ≥98% (HPLC) |
color | , Faint brown to dark red |
form | powder |
Quality Level | 100 ![]() |
SMILES string | CC1=C(CCC(O)=O)/C2=C/C3=N |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | −20°C |
Biochem/physiol Actions: | Stannsoporfin is a potent inhibitor of heme oxygenase 1 (HO-1) and heme oxygenase 2 (HO-2). It inhibits hepatic HO and controls serum levels of bilirubin in infants. Stannsoporfin potently inhibits myeloid HO-1 in tumors. It inhibits immune suppression of chemotherapy-elicited CD8+ T cells. Stannsoporfin concurrently administer with 5-Fluoro uracil produces immediate tumor regression in mice model of breast tumor. |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |