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BC-2059

SIGMA/SML3279 - ≥98% (HPLC)

Synonym: BC 2059; BC2059; Tegatrabetan; Tegavivint; rel-2,7-Bis[[(3R,5S)-3,5-dimethyl-1-piperidinyl]sulfonyl]-9,10-anthracenedione 9,10-dioxime

CAS Number: 1227637-23-1
Empirical Formula (Hill Notation): C28H36N4O6S2
Molecular Weight: 588.74
MDL Number: MFCD32661883
Linear Formula: C28H36N4O6S2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SML3279-25MG
No Price  
45-SML3279-5MG
No Price  
assay ≥98% (HPLC)
color white to beige
form powder
Quality Level 100 
solubility DMSO: 2 mg/mL, clear
storage temp. −20°C
Biochem/physiol Actions: BC-2059 is a cell penetrant, potent and selective inhibitor of the Wnt-signaling pathway that potently inhibits growth of cancer cell lines in vitro. BC-2059 inhibits β-catenin/transducin β-like 1 (TBL1) complex by direct binding to TBL1 complexed with β-catenin. BC-2059 does not inhibit interaction of TBL1 with either NCoR/SMRT or NFkB. It is a potential therapeutic for tumors with deregulated Wnt signaling pathway.
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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