8-nitro-Cgmp Sodium
SIGMA/SML3292 - ≥98% (HPLC)
Synonym: 8-Nitro-guanosine cyclic 3′,5′-(hydrogen phosphate) sodium; 8-Nitro-guanosine 3′,5′-cyclic monophosphate sodium
Empirical Formula (Hill Notation): C10H10N6O9P · Na
Molecular Weight: 412.18
Linear Formula: C10H10N6O9P · Na
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
SMILES string | O[C@@H]1[C@@H]([C@@H](CO2 |
storage temp. | −20°C |
Biochem/physiol Actions: | 8-nitro-cGMP is a second messenger of nitric oxide, which is involved in intracellular redox signaling. 8-nitro-cGMP is a potent inhibitor of tau aggregation. 8-nitro-cGMP induces S-guanylation of tau both in vitro and in tau overexpressed HEK293T cells, which inhibits heparin-induced tau aggregation. |
Purity | ≥98% (HPLC) |
Storage Temp. | −20°C |