UNC6852
SIGMA/SML3324 - ≥98% (HPLC)
Synonym: (2S,4R)
CAS Number: 2688842-08-0
Empirical Formula (Hill Notation): C43H48N10O6S
Molecular Weight: 832.97
Linear Formula: C43H48N10O6S
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
SMILES string | O=C([C@H](C(C)(C)C)NC(CCC |
solubility | DMSO: 2 mg/mL, clear (Warmed) |
storage temp. | 2-8°C |
Biochem/physiol Actions: | UNC6852 is a potent degrader of polycomb repressive complex 2 (PRC2) that targets EED. UNC6852 selectively degrades PRC2 components EED (embryonic ectoderm development), EZH2 (enhancer of zeste homolog 2), and SUZ12 (suppressor of zeste homolog 12) via recruitment of VHL. UNC6852 exhibit anticancer activities in model systems. |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |