Sob-AM2
SIGMA/SML3325 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 2128258-47-7
Empirical Formula (Hill Notation): C21H27NO3
Molecular Weight: 341.44
Linear Formula: C21H27NO3
Product Type: Chemical
assay | ≥98% (HPLC) |
color | white to beige |
form | powder |
Quality Level | 100 ![]() |
SMILES string | CC(C1=C(C=CC(CC2=C(C=C(C= |
solubility | DMSO: 2 mg/mL, clear |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Sob-AM2, sobetirome amide prodrug, is a CNS-penetrating thyromimetic that can access the brain in absence of monocarboxylate transporter 8 (MCT8). New data shows that Sob-AM2 and other thyromimetics stimulates TREM2 (triggering receptor expressed on myeloid cells-2) expression in macrophages and microglia. |
Purity | ≥98% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |