Trofinetide Trifluoroacetate
SIGMA/SML3342 - ≥95% (HPLC)
Synonym: NNZ-2566 Trifluoroacetate; Gly-2–methylPro–Glu Trifluoroacetate; Gly-2MePro-Glu Trifluoroacetate; Glycyl-
Empirical Formula (Hill Notation): C13H21N3O6 · xC2HF3O2
Molecular Weight: 315.32 (free base basis)
Linear Formula: C13H21N3O6 · xC2HF3O2
Product Type: Chemical
assay | ≥95% (HPLC) |
color | white to off-white |
form | powder |
Quality Level | 100 ![]() |
storage temp. | −20°C |
Biochem/physiol Actions: | Trofinetide is a more enzymatically stable analogue of the N-terminal tripeptide of IGF-1(GPE) that exhibits potent neuroprotective effects in varies animal models of neurodegenerative diseases and traumatic brain injury. Trofinetide treatment provides clinically meaningful improvement in Rett syndrome (RTT) and Fragile X syndrome (FXS). |
Purity | ≥95% (HPLC) |
Storage Temp. | −20°C |