Thrombin from bovine plasma
SIGMA/SRE0003 - Suitable for manufacturing of diagnostic kits and reagents
Synonym: Factor IIa
CAS Number: 9002-04-4
EC Number: 232-648-7
MDL Number: MFCD00166053
Product Type: Chemical
application(s) | diagnostic assay manufacturing |
biological source | bovine plasma |
form | powder |
Quality Level | 400 ![]() |
shipped in | wet ice |
specific activity | 80-300 NIH units/mg protein |
storage temp. | −20°C |
Analysis Note: | Activity is expressed in NIH units obtained by direct comparison to a NIH Thrombin Reference Standard, Lot K. |
Analysis Note: | The NIH assay procedure uses 0.2 mL of diluted plasma (1:1 with saline) as a substrate and 0.1 mL of thrombin sample (stabilized in a 1% buffered albumin solution) based on a modification of the method of Biggs. Only clotting times in the range of 15-25 seconds are used for determining thrombin concentrations. |
Biochem/physiol Actions: | Serine protease that selectively cleaves Arg-Gly bonds in fibrinogen to form fibrin and fibrinopeptides A and B. |
Packaging: | 10000, 100000, 250000, 750000 units in glass bottle |
Unit Definition: | Activity is expressed in NIH units obtained by direct comparison to a NIH thrombin reference standard. |
Symbol | ![]() ![]() |
Signal word | Danger |
Hazard statements | H315 - H319 - H334 - H335 |
Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xn |
Risk Statements | 36/37/38-42 |
Safety Statements | 22-24-26-36/37 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
activity | specific activity: 80-300 NIH units/mg protein |
Storage Temp. | −20°C |
Enzyme Commission (EC) Number | 3.4.21.5 ![]() ![]() ![]() ![]() ![]() |
UNSPSC | 12352204 |