γ-Globulins from bovine blood
SIGMA/SRE0011 - Suitable for manufacturing of diagnostic kits and reagents, ≥99% (agarose gel electrophoresis)
Synonym: Bovine γ-Globulin
CAS Number: 9007-83-4
EC Number: 232-706-1
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: SRE0011-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: SRE0011-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: SRE0011-10G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: SRE0011-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: SRE0011-100G
| application(s) | diagnostic assay manufacturing |
| assay | ≥99% (agarose gel electrophoresis) |
| composition | NaCl, ≤4% |
| form | powder |
| Quality Level | 400  |
| shipped in | wet ice |
| storage temp. | −20°C |
| Application: | Bovine γ-globulin has been used as an immunological challenge in studies of mechanisms of immunotolerance. |
| Application: | γ-Globulins from bovine blood has been used along with polyethylene glycol (PEG) to investigate the kinetics of liquid-liquid phase separation (LLPS) in its temporary and arrested state. It has also been used as a parent solution to prevent bacterial growth and study the antibody system with LLPS and highly elevated protein concentrations in arrested transition. |
| Biochem/physiol Actions: | Immunoglobulins are implicated in the activation of the complement system and the opsonization of microbes for phagocytosis |
| General description: | Bovine gamma globulin (BGG) is an important component of the immune system of cows and other bovines. BGG is found in the blood of bovines and is primarily used in the production of medical products such as vaccines, serums, and diagnostic reagents. BGG can also be used to treat certain medical conditions, such as hepatitis B, as well as to boost immunity in humans and other animals. |
| General description: | Plasma protein fraction rich in antibodies |
| General description: | γ-Globulins are immunoglobulins that contain IgM, IgA, and IgY. They are glycoproteins produced by plasma cells. The immunoglobulins are heterodimeric molecules comprising two light chains and two heavy chains linked together by disulfide bonds. |
| Preparation Note: | Prepared from Cohn Fraction II, III |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% (agarose gel electrophoresis) |
| Storage Temp. | −20°C |
| UNSPSC | 12352204 |