Phosphoglucomutase from rabbit muscle
SIGMA/SRE0069
Synonym: α-D-Glucose-1,6-bisphosphatase; α-D-Glucose-1-phosphate phosphotransferase
CAS Number: 9001-81-4
MDL Number: MFCD00131886
Product Type: Chemical
Unit Definition: One unit of phosphoglucomutase will convert 1.0 μmole of α-D-Glucose-1-Phosphate to α-D-Glucose-6-Phosphate per minute at pH 7.4 at 30 °C. The continuous spectrophotometric rate detemination (A340, Light path = 1 cm) is based on the above reactions.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: SRE0069-10KU
| foreign activity | Lactic dehydroenase ≤0.5% |
| Phosphoglucose Isomerase ≤0.01% | |
| pyruvate kinase ≤0.05% | |
| form | lyophilized powder |
| Quality Level | 200  |
| shipped in | wet ice |
| specific activity | ≥100 units/mg protein |
| storage temp. | −20°C |
| Application: | Phosphoglucomutase from rabbit muscle may be used in dephosphorylation to investigate the hexose bisphosphate activation of phosphoglucomutase. |
| Biochem/physiol Actions: | Phosphoglucomutase (PGM) mainly catalyzes the interconversion of glucose 1-phosphate and glucose 6-phosphate via a glucose 1,6-diphosphate intermediate. Hence it plays a key role in glycolysis and gluconeogenesis. |
| General description: | Research area: CellSignalling. The phosphoglucomutase (PGM) molecule, a single polypeptide chain, is made up of four α/β domains. The domains form a compact heart-shaped structure with a large fissure between the two lobes, and the molecule comprises about 40 secondary structural components. The active enzymatic site of the molecule is located at the bottom of the crevice on the surface of domain I. Rabbit muscle phosphoglucomutase (RB-PGM) is a monomer with a unique four-domain architecture. |
| Other Notes: | One unit will convert 1.0 μmole of α- |
| Packaging: | 1000 units in glass bottle |
| Packaging: | 10000 units in poly bottle |
| Physical form: | Lyophilized powder containing Tris HCl, EDTA, magnesium acetate and carbohydrate |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: ≥100 units/mg protein |
| Storage Temp. | −20°C |
| Enzyme Commission (EC) Number | 5.4.2.2 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |