PADI-2 human
SIGMA/SRP0327 - recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE)
Synonym: Peptidyl arginine deiminase, type II
Product Type: Chemical
SDS-PAGE PADI-2 Human : Cat. No. SRP0327: Coommassie blue-stained SDS-PAGE analysis of PADI-2. Lanes 1. 2.6 μg PADI-2. 2. Protein Marker.
Chart PADI-2 Human : Cat. No. SRP0327: Activity assay of PADI-2 Human.
| assay | ≥60% (SDS-PAGE) |
| biological source | human |
| form | aqueous solution |
| mol wt | 77 kDa |
| NCBI accession no. | NM_007365   |
| packaging | pkg of 10 μg |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| storage temp. | −70°C |
| UniProt accession no. | Q9Y2J8 |
| Application: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. PADI-2 human has been used in in vitro binding assays. |
| Biochem/physiol Actions: | Peptidyl arginine deiminase, protein-2 (PADI2) promotes protein citrullination and represses the multiplication of cells. It helps to transform the amino acid arginine in a protein into amino acid citrulline. PADI2 participates in epigenetic mechanisms. It is linked with rheumatoid arthritis. |
| General description: | Human PADI2, also known as Peptidyl arginine deiminase, type II, (GenBank Accession No. NM_007365), amino acids 1-665 (end) with C-terminal FLAG-tag, MW= 77kDa, expressed in a Baculovirus infected Sf9 cell expression system. Peptidyl arginine deiminase, protein-2 (PADI2) is mapped to human chromosome 1p36. It is expressed in Sertoli cells at the time of testicular development. |
| Physical form: | Formulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 ng/uL Flag peptide, 3 mMDTT, and 20% Glycerol. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥60% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |