EZH2 /EED/SUZ12/RbAp48/AEBP2 human
SIGMA/SRP0388 - recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE)
Product Type: Chemical
assay | ≥90% (SDS-PAGE) |
biological source | human |
form | aqueous solution |
mol wt | 48 kDa (AEBP2) |
51 kDa (EED) | |
53 kDa (AEBP2) | |
86 kDa (EZH2) | |
87 kDa (SUZ12) | |
NCBI accession no. | NM_003797 (EED) |
NM_004456 (EZH2) | |
NM_005610 (RbAP48) | |
NM_015355 (SUZ12) | |
NM_153207 (AEBP2) | |
packaging | pkg of 20 μg |
recombinant | expressed in baculovirus infected Sf9 cells |
shipped in | dry ice |
storage temp. | −70°C |
General description: | Inactive mutant version of our regular EZH2 5-member complex, but with a Tyr-to-Cys mutation on amino acids 646 of the EZH2 protein. Complex of human EZH2 (GenBank Accession No. NM_004456), (amino acids 2-end ; Y646C*) with N-terminal His-tag, MW= 86 kDa, human EED (GenBank Accession No. NM_003797) (amino acids 2-end) with N-terminal Flag-tag, MW= 51 kDa, human SUZ12 (GenBank Accession No. NM_015355) (amino acids 2-end) with N-terminal His-tag, MW = 87 kDa, Human AEBP2 (GenBank Accession No. NM_153207) (amino acids 2-end) with N-terminal His-tag, MW= 53 kDa, and human RbAp48 (GenBank Accession No. NM_005610) (amino acids 2-end) with N-terminal His-tag, MW = 48 kDa, coexpressed in Baculovirus expression system. *This mutation is often cited as Y641C in variant 3 (GenBank Accession No. NM_001203247). |
Symbol | GHS07,GHS08 |
Signal word | Danger |
Hazard statements | H315 - H319 - H360D |
Precautionary statements | P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
Hazard Codes | T |
Risk Statements | 61 |
Safety Statements | 53-45 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥90% (SDS-PAGE) |
Storage Temp. | −70°C |
UNSPSC | 12352200 |