EZH2 /EED/SUZ12/RbAp48/AEBP2 human
SIGMA/SRP0388 - recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE)
Product Type: Chemical
SDS-PAGE EZH2 /EED/SUZ12/RbAp48/AEBP2 Human : Cat. No. SRP0388: Coommassie blue-stained SDS-PAGE analysis of enzyme complex. Lanes 1. 12.4 μg enzyme complex. 2. Protein Marker.
| assay | ≥90% (SDS-PAGE) |
| biological source | human |
| form | aqueous solution |
| mol wt | 48 kDa (AEBP2) |
| 51 kDa (EED) | |
| 53 kDa (AEBP2) | |
| 86 kDa (EZH2) | |
| 87 kDa (SUZ12) | |
| NCBI accession no. | NM_003797 (EED)   |
| NM_004456 (EZH2) |
|
| NM_005610 (RbAP48) |
|
| NM_015355 (SUZ12) |
|
| NM_153207 (AEBP2) |
|
| packaging | pkg of 20 μg |
| recombinant | expressed in baculovirus infected Sf9 cells |
| shipped in | dry ice |
| storage temp. | −70°C |
| General description: | Inactive mutant version of our regular EZH2 5-member complex, but with a Tyr-to-Cys mutation on amino acids 646 of the EZH2 protein. Complex of human EZH2 (GenBank Accession No. NM_004456), (amino acids 2-end ; Y646C*) with N-terminal His-tag, MW= 86 kDa, human EED (GenBank Accession No. NM_003797) (amino acids 2-end) with N-terminal Flag-tag, MW= 51 kDa, human SUZ12 (GenBank Accession No. NM_015355) (amino acids 2-end) with N-terminal His-tag, MW = 87 kDa, Human AEBP2 (GenBank Accession No. NM_153207) (amino acids 2-end) with N-terminal His-tag, MW= 53 kDa, and human RbAp48 (GenBank Accession No. NM_005610) (amino acids 2-end) with N-terminal His-tag, MW = 48 kDa, coexpressed in Baculovirus expression system. *This mutation is often cited as Y641C in variant 3 (GenBank Accession No. NM_001203247). |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H315 - H319 - H360D |
| Precautionary statements | P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | T |
| Risk Statements | 61 |
| Safety Statements | 53-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥90% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |