Histone H2a full length human
SIGMA/SRP0406 - recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym: H2AFQ; histone cluster 2, H2ac
Product Type: Chemical
SDS-PAGE Histone H2a full length Human: Cat. No. SRP0406: Coommassie blue-stained SDS-PAGE analysis of Histone H2A. Lanes 1. 4 μg Histone H2A. 2. Protein Marker.
| assay | ≥90% (SDS-PAGE) |
| biological source | human |
| concentration | 1.2 mg/mL |
| form | aqueous solution |
| mol wt | 14.8 kDa |
| NCBI accession no. | NM_033445   |
| packaging | pkg of 1 mg |
| recombinant | expressed in E. coli |
| shipped in | dry ice |
| storage condition | avoid repeated freeze/thaw cycles |
| storage temp. | −70°C |
| UniProt accession no. | Q16777 |
| Biochem/physiol Actions: | Histone cluster 2 H2A family member c (HIST2H2AC) has a role in maintaining the structure of the chromatin. |
| Biochem/physiol Actions: | Histone cluster 2 H2A family member c (HIST2H2AC) participates in multiple epigenetic regulations and carcinogenesis. It also participates in embryonic stem (ES) cell biology and regulates the expression of genes. It modulates proliferation and epithelial-mesenchymal transition in mammary epithelial and breast cancer cells. Hist2h2ac also controls epithelial differentiation. |
| General description: | Histone cluster 2 H2A family member c (HIST2H2AC) is located on human chromosome 1q21. It is usually present in undifferentiated/prolifer |
| General description: | Histones make up the nucleosome, which is the fundamental unit of the chromatin. Each nucleosome consists of 146 base pairs of DNA which is wrapped around an octamer of four core histones H2A, H2B, H3 and H4. Histone cluster 2 H2A family member c (HIST2H2AC) has many variants. Human Histone 2A (GenBank Accession No. NM_033445) amino acids 2-130 (end) with N-terminal His-tag, MW = 14.8 kDa, expressed in an E. coli expression system. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥90% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |