N-CoR human
SIGMA/SRP2073 - recombinant, expressed in insect cells, ≥60% (SDS-PAGE)
Synonym: KIAA1047; MGC104216; N-CoR; N-CoR1; TRAC1; hN-CoR
Product Type: Chemical
| assay | ≥60% (SDS-PAGE) |
| biological source | human |
| color | clear colorless |
| concentration | 700 μg/mL |
| form | frozen liquid |
| mol wt | ~271 kDa |
| NCBI accession no. | NM_006311   |
| packaging | pkg of 5 μg |
| recombinant | expressed in insect cells |
| shipped in | dry ice |
| storage temp. | −70°C |
| technique(s) | deacetylase assay: suitable |
| UniProt accession no. | O75376 |
| Biochem/physiol Actions: | This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined |
| Physical form: | Clear and colorless frozen liquid solution |
| Preparation Note: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥60% (SDS-PAGE) |
| Storage Temp. | −70°C |
| UNSPSC | 12352200 |