RNA Polymerase II, C-terminal domain, GST tagged human
SIGMA/SRP2120 - recombinant, expressed in E. coli, ≥70% (SDS-PAGE)
Synonym: POLRA; RPB1; RPO2; RPOL2; hRPB220
Product Type: Chemical
assay | ≥70% (SDS-PAGE) |
biological source | human |
color | clear colorless |
form | frozen liquid |
mol wt | ~68.1 kDa |
NCBI accession no. | NM_000937 |
packaging | pkg of 10 μg |
recombinant | expressed in E. coli |
shipped in | dry ice |
storage condition | avoid repeated freeze/thaw cycles |
storage temp. | −70°C |
UniProt accession no. | P24928 |
Biochem/physiol Actions: | The carboxy-terminal repeat domain (CTD) of the largest subunit of RNA pol II contains tandem repeats of a heptapeptide sequence Tyr-Ser-Pro-Thr-Ser-Pro-S |
Biochem/physiol Actions: | The CTD works as a binding scaffold for nuclear factors through its phosphorylation. It is suggested to be also involved in chromatin structure modification, DNA damage/repair, protein degradation and synthesis, RNA degradation, snRNA (small nuclear RNA) modification, and snoRNP (small nucleolar ribonucleoprotein) biogenesis. |
Physical form: | Clear and colorless frozen liquid solution |
Preparation Note: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥70% (SDS-PAGE) |
Storage Temp. | −70°C |
UNSPSC | 12352200 |