FGF-16 human
SIGMA/SRP3038 - recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture
Synonym: FGFG; Fibroblast Growth Factor-16
Product Type: Chemical
| assay | ≥95% (HPLC) |
| ≥95% (SDS-PAGE) | |
| biological source | human |
| color | white to off-white |
| form | lyophilized |
| impurities | <0.1 EU/μg endotoxin, tested |
| mol wt | 23.7 kDa |
| packaging | pkg of 25 μg |
| potency | ≥2x10^6 units/mg |
| recombinant | expressed in E. coli |
| shipped in | wet ice |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| UniProt accession no. | O43320   |
| Biochem/physiol Actions: | Fibroblast growth factor-16 (FGF-16) signals through FGFR 2c and 3c. FGF-16 plays a role in the development of the central nervous system. This protein has a positive effect on mitosis and cell survival. FGF-16 also has roles in tissue repair, embryonic development, morphogenesis and tumor growth. |
| General description: | Fibroblast growth factor-16 (FGF-16) is a heparin binding growth factor that is a member of the FGF9 subfamily. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. Recombinant human FGF-16 is a 23.7 kDa protein consisting of 207 amino acid residues. |
| Physical form: | Lyophilized from 5 mM sodium phosphate, pH 9.0, containing 0.1 M L-arginine and 0.4 mM DTT. |
| Reconstitution: | Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.5-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C. |
| Sequence: | MAEVGGVFAS LDWDLHGFSS SLGNVPLADS PGFLNERLGQ IEGKLQRGSP TDFAHLKGIL RRRQLYCRTG FHLEIFPNGT VHGTRHDHSR FGILEFISLA VGLISIRGVD SGLYLGMNER GELYGSKKLT RECVFREQFE ENWYNTYAST LYKHSDSERQ YYVALNKDGS PREGYRTKRH QKFTHFLPRP VDPSKLPSMS RDLFHYR |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC); ≥95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |