GRO/KC (CXCL1) from rat
SIGMA/SRP3240 - recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Synonym: CINC; CXCL1; GRO?; NAP-3
Product Type: Chemical
assay | ≥98% (HPLC) |
≥98% (SDS-PAGE) | |
biological source | rat |
color | white to off-white |
form | lyophilized |
impurities | <0.1 EU/μg endotoxin, tested |
mol wt | 7.8 kDa |
packaging | pkg of 25 μg |
potency | 10.0-100.0 ng/mL |
recombinant | expressed in E. coli |
shipped in | wet ice |
storage temp. | −20°C |
technique(s) | cell culture | mammalian: suitable |
UniProt accession no. | P14095 ![]() ![]() |
Biochem/physiol Actions: | All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. Recombinant rat KC is a 7.8 kDa protein consisting of 72 amino acids including the ‘ELR’ motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. |
General description: | All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat KC is a 7.8 kDa protein consisting of 72 amino acids including the ‘ELR’ motif common to the CXC chemokine family that bind to CXCR1 or CXCR2. |
Physical form: | Lyophilized with no additives. |
Reconstitution: | Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C. |
Sequence: | APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98% (HPLC); ≥98% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |