IP-10 from rat
SIGMA/SRP3246 - recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Synonym: CXCL10; crg-2; g-Interferon Inducible Protein 10
Product Type: Chemical
assay | ≥98% (HPLC) |
≥98% (SDS-PAGE) | |
biological source | rat |
color | off-white to yellow |
form | lyophilized |
impurities | <0.2 EU/μg endotoxin, tested |
mol wt | 8.6 kDa |
packaging | pkg of 25 μg |
recombinant | expressed in E. coli |
shipped in | wet ice |
storage temp. | −20°C |
technique(s) | cell culture | mammalian: suitable |
UniProt accession no. | P48973 ![]() ![]() |
Biochem/physiol Actions: | IP-10 is a CXC chemokine that signals through the CXCR3 receptor. Recombinant rat IP-10 is an 8.6 kDa protein containing 77 amino acid residues, including the four conserved cysteine residues present in CXC chemokines. |
General description: | IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant rat IP-10 is an 8.6 kDa protein containing 77 amino acid residues, including the four conserved cysteine residues present in CXC chemokines. |
Physical form: | Lyophilized with no additives. |
Reconstitution: | Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C. |
Sequence: | IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMKKNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Purity | ≥98% (HPLC); ≥98% (SDS-PAGE) |
Storage Temp. | −20°C |
UNSPSC | 12352200 |