INSL5/INSL7 HYBRID human
SIGMA/SRP3304 - recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)
Synonym: none
Product Type: Chemical
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| assay | ≥98% (HPLC) |
| ≥98% (SDS-PAGE) | |
| biological source | human |
| color | white to off-white |
| form | lyophilized |
| impurities | <0.1 EU/μg endotoxin, tested |
| mol wt | 5.7 kDa |
| packaging | pkg of 25 μg |
| recombinant | expressed in E. coli |
| shipped in | wet ice |
| storage temp. | −20°C |
| UniProt accession no. | Q9Y5Q6 / Q8WXF3   |
| Biochem/physiol Actions: | The Insulin/Relaxin structural family of proteins consists of at least seven members, each containing an Insulin-like hetero-dimeric structure consisting of two polypeptide chains held together by two inter-chain disulfide bonds. INSL7-INSL5 hybrid contains the B-chain of INSL7 (Relaxin-3), linked to the A-chain of INSL5. The INSL7-INSL5 hybrid protein can specifically activate the G protein coupled receptors, GPCR135 and GPCR142, but unlike Relaxin-3, does not induce significant activation of the LGR7 receptor. Recombinant INSL7-INSL5 hybrid is a hetero-dimeric 5.7 kDa protein consisting of a 27 amino acid B-chain disulfide linked to a 21 amino acid A-chain. |
| Physical form: | Lyophilized with no additives. |
| Preparation Note: | Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC); ≥98% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |